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Viagra (Sildenafil citrate), which millions of men take for erectile dysfunction (ED), reduces the effects of hormonal stress on the heart by half, according to a study published online in the journal Circulation. Viagra causes genital blood vessels to expand, which helps in maintaining an erection. Recent research also has pointed to its potential usefulness in treating pulmonary hypertension. Prior to the latest findings by a team of Johns Hopkins researchers, it was thought to have little effect on the heart. Viagra, or sildenafil, blunts the strengthened heart beat caused by chemically induced stress, according to study senior author and cardiologist David Kass, MD, a professor at the Johns Hopkins University School of Medicine and its Heart Institute. It thereby lessens both the excess amount of blood and the force used to pump it to the body. "Sildenafil effectively puts a 'brake' on chemical stimulation of the heart," says Kass. Prevents and Reverses Effects of High BP These findings are believed to be the first confirmation in humans that Viagra has a direct effect on the heart. In earlier research, Kass and his team observed a similar effect in mice; Sildenafil blocked the short-term effects of hormonal stress in the heart. Related studies by the group show that sildenafil also prevents and reverses the long-term effects of chronic high blood pressure on the heart. Sildenafil reversed the negative effects on heart muscle weakened by heart failure and enlargement -- a condition called hypertrophy -- in mouse experiments Kass and his team carried out earlier this year. They reported their results in the journal Nature Medicine. "But we had no firm evidence as to whether or how this therapy might work in the human heart," says Kass. "Our latest research provides firm evidence this drug does indeed have an important impact on the heart." Increased Heartbeat Was Slowed Thirty-five healthy men and women, with an average age of 30 and no previous signs of coronary artery disease, participated in the six-month Johns Hopkins study. Within a three-hour timeframe, each participant received two separate injections of dobutamine (5 micrograms per kilogram for five minutes), a synthetic, adrenaline-like chemical that increases heart rate and pumping strength. Between injections, study participants were assigned randomly to a group that was treated with sildenafil (100 milligrams taken orally) or to a group given a sugar pill placebo. All participants then were given the second dobutamine injection to see what effects sildenafil or placebo had on the heart. Measurements of heart function were made before and after each injection. These included blood pressure readings, electrocardiograms and echocardiograms. Blood samples confirmed relatively equal levels of sildenafil and other enzymes. Each dobutamine injection stimulated heart function, increasing heart rate and the force of each heartbeat used to pump blood throughout the body, results showed. "This stimulation is similar to the way the nervous system normally increases heart function when triggered by emotional or exercise stress, or in diseases such as heart failure," notes Kass. After the first injection of dobutamine, the force of heart contraction increased by 150 percent in both groups. In the placebo group, this increase repeated itself after the second injection. However, in the group treated with sildenafil, the increased heartbeat was slowed by 50 percent, resulting in a smaller increase in blood flow and blood pressure generated by the heart in response to chemical stimulation. Between injections, heart function was not altered in the sildenafil group, demonstrating the absence of adverse side effects on the resting human heart. Stops PDE5A Action "Knowing more about the effects of sildenafil on heart function will allow for safer evaluation of its use as a treatment for heart problems," says Kass. "Our results set the stage for further studies of sildenafil's immediate and long-term effects on the heart and its ability to modify other neurohormonal and stress stimuli, including adrenaline and hypertension," he adds. While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), Kass explains. This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart. PDE5A is also the biological pathway that sildenafil blocks in the penis to prevent the relaxation of blood vessels and thus maintain erections. Copyright 2005 Daily News Central best enargement exercise penis free penis enlagement pills real penis enhancement herbal natural penile enlargement penis enlargement program enlargement manhattan pennis surgeon manual pnis enlargement exercise penis enhancement pills product
What is a varicocele? A varicocele is a swollen vein in the scrotum. Normal veins in the scrotums are usually constricted and not dilated. In varicocele, the veins in the scrotums are dilated. Varicoceles are more commonly found in the left scrotum than then in the right due to anatomic factors. Varicocele is a well-known cause of subnormal testicular function and can be found in approximately 20-25% of all males and in 40% of infertile males. As a matter of fact, varicocele is the leading cause of infertility in males. Varicoceles are easy to detect and can be easily corrected by surgical interventions. Varicoceles are much more common in the left scrotum (80-90%) than in the right as a result of several anatomical factors. Also of importance is that right-sided varicoceles should be carefully investigated as more often than not, a right-sided varicocele may indicate cancer of the right kidney. How do I know I'm affected by varicocele? A varicocele feels like a "bag of worms". Contrary to what most people believe, varicoceles usually do not cause any pain, but swelling of the scrotum, be it in one or both sides. Other problems that have to be excluded, that may cause scrotum enlargement include fluids in the scrotum, testicular cancer, a cyst or spermatocele, etc. In general, varicoceles are harmless, are not cancerous, although in the long run, they may give rise to infertility. Some health professionals believe that if left untreated, they may even cause cancer of the testicles. What are the long term complications of untreated varicocle? If left untreated, varicoceles may give rise to several problems: 1. Testicular atrophy (or shrinkage) 2. Infertility 3. Testicular cancer (rare) How is a varicocele diagnosed? Varicocele is diagnosed clinically by testicular examination. Alternatively, if a diagnosis of varicocele is uncertain, high-resolution color-flow Doppler ultrasonography is the diagnostic method of choice. What are the treatment options available for varicoceles? Medical therapy has no place in the treatment of varicoceles. The main form of treatment for varicocle is surgery. However, the presence of a varicocele does not necessarily need surgical correction. Having said that, if treatment is indicated, surgical correction is the treatment of choice. There are several methods of surgical corrections, these include microscopic sub-inguinal varicocelectomy, inguinal varicocelectomy, retroperitoneal varicocelectomy and laparascopic varicocelectomy. In most cases, the patient is sedated. What lifestyle changes can be carried out to optimize semen quality and quantity? There are ways for sufferes of varicoceles to improve their semen quality and quantity by life style changes, these include: 1. Quit smoking 2. Avoid use of marijuana 3. Avoid use of cocaine 4. Avoid use of anabolic steroids 5. Reduce alcohol intake 6. Avoid lubricants 7. Increase aerobic exercises. penis enlagement pump best penis enlargment surgery penile enlargment before and after photo vimax penis enlargement surgery picture penis girth enlarement penis elargement surgeon vimax herbal penis enlargement pills surgical pennis enlargement penis enhancement traction device
To give a women pleasure, it is important to understand the stages of the female orgasm and what they mean to give your partner pleasure and satisfaction. In Western terms, the female orgasm is (from the Greek orgasmos, "to swell"), is also known as the sexual climax; a pleasurable physical, psychological and emotional response to prolonged sexual stimulation. A female orgasm, like the male one, is often accompanied by a notable physiological reaction, such as blushing with or without spasms and may be followed by additional spasms known as aftershocks. In the East, as described in the Chinese Tao of sex, the female orgasm is far more categorized, and is said to have 9 stages. Most men (from the East and West) who are not aware of the 9 stages often stop at stage 4, thus depriving the woman of the ultimate pleasure available to her. The 9 stages are as: The 9 stages of female orgasm 1. The “lung” stage, where the woman “sighs”, breathes very heavily and salivates. 2. The “heart” stage where the woman is kissing her man often extending her tongue out to him. 3. The “spleen, pancreas, and stomach” stage where the woman’s muscles become tense, and she grasps her man tightly. 4. The “kidney and bladder” stage where the woman experiences a series of vaginal spasms, and she will have much vaginal secretion simultaneously. The untrained man believes this is the climax. 5. The “bone” stage, where the woman’s joints loosen and she will bite her partner. 6. The “liver and nerve” stage, where the woman moves like a snake under or over her man, and she will wrap her arms and legs around him. 7. The “blood” stage, where the woman’s blood feels like it is boiling and she is grasping her man everywhere. 8. The “muscle” stage, where the woman’s muscles totally relax, but she is known to grasp even more and bite the man’s nipples. 9. The “complete body” stage, where the woman finally collapse, and feels what is known as the little death. Psychological stages of the female orgasm Certainly the Eastern approach to a female orgasm is far more organized than just a “sexual climax”. But looked at more carefully, lets understand what is happening physiologically. The female orgasm is preceded by moistening of the vaginal walls, and an enlargement of the clitoris due to increased blood flow trapped in the clitoris's spongy tissue. Many women exhibit a sex flush; a reddening of the skin over much of the body due to increased blood flow to the skin. As a woman approaches her orgasm, her clitoris retracts under the clitoral hood, and the labia minora (minor lips) becomes darker (due to blood swell). As her orgasm becomes imminent, the vagina decreases in size from 25% to 40% and also becomes congested from engorged soft tissue. The uterus can then experiences muscular contractions. A woman experiences full orgasm (in Western terms) when her uterus, vagina and pelvic muscles undergo a series of rhythmic contractions. The majority of women consider these contractions to be very pleasurable. It is at this point, Western and Eastern conceptions differ. In Western thought, after the orgasm is over, the clitoris re-emerges from under the clitoral hood, and returns to its normal size in less than 10 minutes. Multiple female orgasms Unlike men, women either do not have a refractory period or have a very short one, and thus can experience a second orgasm soon after the first; some women can even follow this with additional consecutive orgasms, up to eight have been reported amongst some people; this is known as having multiple orgasms. In Eastern thought, these are just part of the process. Again, in Western thought, a distinction is sometimes made between a clitoral and a vaginal orgasm. A female orgasm that results from combined clitoral and vaginal stimulation is called a blended orgasm. In Eastern thought, this is getting closer to stage 9. A final consideration is the case of female ejaculation. It is not considered at all in Eastern thought, but in the West there is a long-standing discussion about the existence of Female ejaculation (colloquially known as squirting or gushing). This refers to the expulsion of noticeable amounts of fluid from the urethra or vagina during sexual stimulation at or near orgasm. The expelled fluid is reported variously as: • Urine, possibly due to stress incontinence, • A clear or milky fluid which emerges (sometimes with force), has a composition similar to the fluid generated in males by the prostate gland, and is generated by Skene's glands, or • A mixture of these two fluids. • None of the above, but only an excess of vaginal lubricating fluids, and is a concept used to support feminist theory or the stuff of interest for porno films. The fact is the female orgasm goes through various stages knowing what these stages are and what to expect means that you can respond and guide you women to ultimate satisfaction. Find out how to help your women orgasm in part 2 This is discussed in part 2 “helping your women reach orgasm every time” natural penis enhancement magna rx vimax penis enlargement fact penile enlargement pills review penis enhancement before and after picture pennis enlargement technique pnis enlargement system vimax penis enlargement operation penis enhancement traction device
You can do a Google search for “Viagra jokes” and turn up over 30,000 webpages. But as most men (and women) know, erectile dysfunction (sometimes called ED or impotence) is no joke. Every guy has had a time where he cannot have or sustain an erection. The flu, exhaustion, a long bout of sex with no breaks, even other worries (work, finances, even sexual performance anxieties) can affect erectile abilities. For some men, though, ED can become a recurring problem. Diabetes, high blood pressure, or clogged arteries can reduce blood flow to the penis. ED can also be caused by physical blockages (like prostate enlargement), hormonal imbalance, or medications (like antidepressants). For about 20% of men with ED, psychological issues may be contributing to the problem. It’s important to realize that many of these causes have nothing to do with age! If you are experiencing problems with ED, it doesn’t mean you’re getting “old” – think of it as your body signaling for a change! Fitting Viagra Into the Picture For many of the causes of ED, managing the underlying illness or problem will be enough to improve sexual function. In some cases, however, Viagra can help with sexual activity. Viagra works on some of the muscles in your penis that help control the blood flow (when we’re teens, the control over these muscles isn’t always perfect which is why erections would sometimes pop up at inconvenient moments). Viagra encourages these muscles to let more blood flow into the penis when the time is right. The effect can last up to four hours, so taking Viagra the day that you would like to have sex will ensure that it can work effectively for you. Don’t worry that it will cause you to have an erection before you are ready for one – it works in conjunction with sexual stimulation. Viagra Does Not Increase Sex Drive While Viagra assists with developing with erections, it is not an aphrodisiac. In other words, it helps with the mechanics but not sex drive. If you don’t feel like having sex, the drug isn’t going to change your mind! Many men, however, do find that as they feel more confident about their ability to gain and maintain an erection they feel happier about being physically intimate. Viagra can also have side effects; many are mild (indigestion and flushing) but a few are serious, so make sure your doctor gives you a list of things to look out for! Mix and Match Safely Because Viagra is a very potent drug, your physician will ask you lots of questions before pulling out his prescription pad. Because Viagra affects your blood flow, if you have significant heart problems, history of stroke, or untreated diabetes or high blood pressure, Viagra may not be the best match for your other health needs. Many drugs that affect your heart and circulation can interact in very harmful ways with Viagra, so make sure to take a list of all the drugs you’re taking with you when you visit the doctor. Lastly, if you use recreational drugs, do yourself a favor and speak frankly with your doctor – he’ll keep it confidential – because some of these drugs (including “poppers” or amyl nitrate) can be a fatal mix with Viagra. Are you ready? If you’ve been experiencing ED you’re ready to take the next step –see your doctor to find out if Viagra is right for you! penile enlargment pic before and after vimax enlargement forum free matter penis size pennis enlargement pic before and after penis enhancement program truth about penis enlargement pill penile enlargment surgeon buy place vigrx vimax penis enlargement system penis enhancement traction device
Whether at work or under the cover, men are under constant pressure to perform. Unfortunately, both men and women can place too much importance on this, and search out the fastest, easiest answers. Fortunately there's an alternative. By arming ourselves with information on the newest natural options, we can choose the best treatment for our individual needs. Viagra's fishy replacement? By now if you've heard of Bob Dole you've heard of Viagra. But have you heard of Irukandji? This soft and toxic jellyfish may soon be giving Viagra, and men everywhere, a very hard time. A sting from Irukandji causes intense pain in the limbs, cramps, vomiting, difficulty breathing, anxiety, and sometimes cardiac and lung problems. However, it also causes prolonged erection. Currently, this is a lousy trade off. Realizing this, Australian researcher Lisa Gershwin is attempting to separate the erection-causing feature. But don't be tossing your little blue pills just yet. More Irukandji need to be studied before an impotency medication can be manufactured. X-rated chewing gum Those wanting to build stronger sperm now have more options than loose boxers and cool temperatures. A simple green African plant may boost the power of the troops down under. Call it a miracle. Call it the khat plant. Lab tests at London's King College have found that sperm treated with cathine, a chemical in khat, became fertile faster and stayed that way longer. Though so far the studies are only on mice and rabbits, early human tests suggest a similar result. But before you get too excited, it's worthwhile knowing that potency through khat's cathine is currently the domain of researchers. Why? Munching on khat has potentially dangerous side effects like delusions and elevated pulse and blood pressure. Due to this, the current focus is on finding the right cathine concentration, and making sure it's safe for more than mice. Just breathe Occasional impotence is common and often caused by anxiety. Long term failure to function, though, is another matter. According to the UK's Sexual Dysfunction Association: "Until about 20 years ago, erectile dysfunction was considered to be caused almost entirely by psychological factors but we now know that physical conditions are present in about 75% of male sufferers." So unless you're very young or very stressed, impotence is probably not in your head. However, it may be in your glans. The glans, or head of the penis, needs a strong and constant flow of blood to stay stiff. This requires effective circulation. In short, if your blood isn't moving neither will your penis. Speedier circulation can be gained through a healthy diet and aerobic exercise. Deep breathing is another way to circulate. By bringing more blood to the lungs, more blood goes to the heart. This is a sweat-free way to strengthen both blood flow and phallus. P.C. isn't just politically correct Finding and working the PC, or pubococcygeus muscle, is a sure way to satisfy you and your partner. If you've ever had to stop in mid-stream while urinating, you've already exercised it. This muscle has another use. Training it develops sexual power. Authors of The Multi-Orgasmic Man; Mantak Chia and Douglas Abrams Arava, state that training this muscle helps "strengthen your erections, intensify your orgasms, and separate your orgasms from ejaculation." To pump this muscle up, first locate it. Most men feel this muscle at their perineum, behind the testicles and ahead of the anus. Now inhale and focus on the prostate, perineum and anus. Next exhale and squeeze the muscle around your anus and prostate. Then release and relax. According to The Multi-Orgasmic Man, this exercise should be repeated 9 to 36 times. Performance plus Though it often takes center stage, the penis an overrated performer. Satisfying a woman also involves foreplay and sensitivity to her needs. No matter how potent you are, if these two things aren't also considered your partner will be looking at her watch rather than into your eyes.