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Viagra (Sildenafil citrate), which millions of men take for erectile dysfunction (ED), reduces the effects of hormonal stress on the heart by half, according to a study published online in the journal Circulation. Viagra causes genital blood vessels to expand, which helps in maintaining an erection. Recent research also has pointed to its potential usefulness in treating pulmonary hypertension. Prior to the latest findings by a team of Johns Hopkins researchers, it was thought to have little effect on the heart. Viagra, or sildenafil, blunts the strengthened heart beat caused by chemically induced stress, according to study senior author and cardiologist David Kass, MD, a professor at the Johns Hopkins University School of Medicine and its Heart Institute. It thereby lessens both the excess amount of blood and the force used to pump it to the body. "Sildenafil effectively puts a 'brake' on chemical stimulation of the heart," says Kass. Prevents and Reverses Effects of High BP These findings are believed to be the first confirmation in humans that Viagra has a direct effect on the heart. In earlier research, Kass and his team observed a similar effect in mice; Sildenafil blocked the short-term effects of hormonal stress in the heart. Related studies by the group show that sildenafil also prevents and reverses the long-term effects of chronic high blood pressure on the heart. Sildenafil reversed the negative effects on heart muscle weakened by heart failure and enlargement -- a condition called hypertrophy -- in mouse experiments Kass and his team carried out earlier this year. They reported their results in the journal Nature Medicine. "But we had no firm evidence as to whether or how this therapy might work in the human heart," says Kass. "Our latest research provides firm evidence this drug does indeed have an important impact on the heart." Increased Heartbeat Was Slowed Thirty-five healthy men and women, with an average age of 30 and no previous signs of coronary artery disease, participated in the six-month Johns Hopkins study. Within a three-hour timeframe, each participant received two separate injections of dobutamine (5 micrograms per kilogram for five minutes), a synthetic, adrenaline-like chemical that increases heart rate and pumping strength. Between injections, study participants were assigned randomly to a group that was treated with sildenafil (100 milligrams taken orally) or to a group given a sugar pill placebo. All participants then were given the second dobutamine injection to see what effects sildenafil or placebo had on the heart. Measurements of heart function were made before and after each injection. These included blood pressure readings, electrocardiograms and echocardiograms. Blood samples confirmed relatively equal levels of sildenafil and other enzymes. Each dobutamine injection stimulated heart function, increasing heart rate and the force of each heartbeat used to pump blood throughout the body, results showed. "This stimulation is similar to the way the nervous system normally increases heart function when triggered by emotional or exercise stress, or in diseases such as heart failure," notes Kass. After the first injection of dobutamine, the force of heart contraction increased by 150 percent in both groups. In the placebo group, this increase repeated itself after the second injection. However, in the group treated with sildenafil, the increased heartbeat was slowed by 50 percent, resulting in a smaller increase in blood flow and blood pressure generated by the heart in response to chemical stimulation. Between injections, heart function was not altered in the sildenafil group, demonstrating the absence of adverse side effects on the resting human heart. Stops PDE5A Action "Knowing more about the effects of sildenafil on heart function will allow for safer evaluation of its use as a treatment for heart problems," says Kass. "Our results set the stage for further studies of sildenafil's immediate and long-term effects on the heart and its ability to modify other neurohormonal and stress stimuli, including adrenaline and hypertension," he adds. While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), Kass explains. This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart. PDE5A is also the biological pathway that sildenafil blocks in the penis to prevent the relaxation of blood vessels and thus maintain erections. Copyright 2005 Daily News Central pnis enlargement surgery manual penis enlargement exercise natural pennis enlargement pills buy penis enlarement pills pnis enlargement herb free penis enlargment pills natural penis enlarement and lengthening free exercise tip for penis enlagement

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My humble relationship advice for women at 40. Recently, I had the opportunity to play a round of golf with a female friend of mine and two of her female friends as well. After a great round of golf, we went back to her house where I proceeded to cook dinner for all of us. Because I was a friend, male and cooking dinner, the ladies seemed to feel very comfortable talking in front of me about their dating lives. Holy cow. What an eye opener that was. Let me first start by saying, I am not all that and a bag of chips -far from it actually. I have my hang ups and feel the normal insecurities most of us face on a daily basis. What I heard and experienced that fateful night at dinner almost made me run screaming from the house. As the night progressed and wine flowed, I began to see a side of this group of three women that had me questioning if I would ever date again. I have never heard a group of people bitch and gripe about so many people in my entire life. They looked like three Queens, sipping red wine and damning the rest of us who happen to be male to the guillotine. I felt like asking them if they saw any correlation between the fact they had such impossibly high standards for men and the fact they were all single themselves. Furthermore, it appeared this group of forty something women had never had a serious relationship, either past or present, where they seemed sincerely happy. I am not suggesting all women are like this. If however, you find you are approaching forty or on the North side of forty, single and without any prospects for any kind of date soon, you may want to consider the following advice. If you are looking for perfection from a man then you damn well better bring perfection to the table yourself. These three women were holding up impossibly high standards that no man could realistically attain. One woman in the group was obviously very good looking, had a good job, loved golf and seemed very bright. There was a litany of stories from her about failed relationships and unsuccessful dating experiences. Nice guy, cute, clean and neat, great job but drove a crappy car. Perhaps he didn’t see the value in wasting money on a sports car? Perhaps he valued saving some of his money for later in life? Great guy, great job and great everything else but had a weird haircut and ear hair. Awesome guy, sincere, respectful, bright, witty and charming but was not well enough endowed. I’m not suggesting women settle for any reason. None of us should do that. I am saying that we all need to set realistic expectations of what we are looking for in a date. What would happen if the great guy with the crappy car were given a chance to explain himself? What would happen if Mr. Awesome with the small penis had a good friend who could make livestock weep and cry? If they had given any of these guys half a chance, they may have found their potential dating circle may have expanded nicely. I have no trouble getting dates. It’s not because I am the best looking guy, with a great body, a million dollar bank account, a fantastic car and I could stand in for Ron Jeremy. I get dates because I realize I am far from perfect but I am a sincerely nice person. My expectations for myself are realistic and more importantly, I set realistic expectations for my dates. We have all heard women pine for the good guys in a relationship, wondering where they are. How come there are no good guys left they seem to constantly complain. There are nice guys out there. They do exist! Ladies, you need to give some of us a chance. Dating is a lot like poker; you have to know how to play the cards you have been dealt. You can only bluff for so long. If these women continue to play their hands the way they have been going, it is only a matter of time before someone calls their hand. guide to penis enlagement penis elargement before and after penis enlargement technique penis enargement pills product penis enhancement patch male penis enhancement penis elargement result free exercise tip for penis enlagement best enlargement exercise penile

Why is it that men cheat? Brad Pitt was married to the woman idolized as everyone’s best friend Jennifer Anniston and the next thing we know he’s coming out of a mud hut in Namibia carrying Angelina Jolie’s 2 children. Hugh Grant was with the most beautiful woman on earth Elizabeth Hurley and the next thing you know the police find him in the back seat of a Chevy with a hooker who looks like Marvin Hagler wearing a wig. Elizabeth Taylor has been cheated on by so many husbands that she needed the pain medication more for her depression than for her aching back. The classic example was Marilyn Monroe who was treated like Kleenex by more Presidents than George Bush. Why do so many Presidents have names that sound like female sexual organs? How many organ grinders does it take to change a monkey? It seems like having supernatural beauty, fame and success drives men to cheat. How could this be? Why are men running away from the women most desired by hordes of men? Barbara Holdmee works in the web cam business in Amsterdam. She nude video chats with strange men all day for $4.99 a minute. According to Barbara, “I used to be a high school English teacher. The hours were long and the pay was lousy. I learned that Men are from Mars, Women are from Venus and teenagers are from Uranus. But this web cam business has really opened my eyes. When you watch Tucker Carlson on television men seem so intelligent, so sophisticated. In the nude video chat sessions you get to see what men are really like. Before nude chat I seduce the men by chatting in a negligee. All day I listen to a constant stream of instant messages from men like “Show me your rear end, show me your boobs, oh BB you’re so hot, and Oh yeah BB. Why do men feel the need to put on this air of sophistication in public? Why can’t they be themselves in public? Why are married men spending an average of 7 minutes a day engaging in sexual relations with nude models over the internet? Who threw Natalie Wood to the sharks? Could the reason that men cheat simply be that in truth they are just wolves in sheep’s clothing, evil liars?” Sigmund Freud, the father of modern psychiatry had a long term affair with his mother. He cheated on her with his sister. Dr. Freud divided the human brain into the ego and the id. There is so much id theft on the internet now that identity theft has become the leading industry in Africa. In the past week alone I have inherited over $356 million dollars from total strangers overseas. I have more parents and grandparents than the descendants of the Messiah. How are there so many paintings of the Messiah when the Gospels do not contain one single word of description of Jesus Christ? Which species was created by a Jewish born Rabbi whose best friend was a hooker? Had Jesus lived to be 85 the ceiling of the Sistine Chapel would be decorated with paintings of a long bearded black hatted black coated Hasidic Rabbi Messiah and Christianity would never have gotten off the ground. Speaking of the Bible Eve has been smeared for 3,000 years for giving Adam the apple. This Bible story is symbolic. The one eyed snake who told her to do it was Adam’s phallus. The penis is the root of all evil. How else can you explain the level of promiscuity in Africa when the obvious cure for AIDS is monogamy? How else can you explain the male stampede for Viagra and Cialis when these drugs are known to cause blindness? Does everyone believe that they will die tomorrow and so there is no need to consider the consequences of their actions? Fortunately Merck has just invented a vaccine for cervical cancer and the human papiloma virus. Get down! Get down, get down, get down, get down, get down tonight baby! “Why dost thou seeketh to be that which thou are not?” Most men have a body, a mind and a soul. Lets look at the body first. A good example would be Michelangelo’s The David. Dr. Freud said that men have a sexual thought every 3 seconds. This would explain the Holy Trinity. With the constant production of semen going on in the testes and the male reproductive drive to keep our species going men are unto coitus machines careening out of control. Now let us look at the human mind. The id is the part of the brain that constantly wants food, sex, money etc. In the old days the strongest cave man just beat the object of his desire over the head with a wooden club and then dragged her into a cave and raped her before lighting up. There were no $200 dinners where the cave man pretended to like her. The reason that men cheat is the male ego. The male ego is the root of all evil. The male feeling of desire and lust and infatuation and desire to conquer the woman and the newness feels exactly like love only it is infinitely stronger. This is why prior to the conquest men whisper such endless baloney into our ears. “Oh my God you are the most beautiful woman I have ever seen in my entire life. I could care less about sex. I love you for your personality.” The micro second that the man ejaculates inside of you without a condom because his passion was so overwhelming and his promises that he was in perfect health were so convincing it’s all down hill even for the Holy Wood starlets. This is because the woman will never again be able to give the man the one thing he wants most in life – the conquest of her - the need in the male mind to say to himself and to his locker room buddies, “Yes, I nailed her!” Nailed? Every single woman that I know today is engaged in internet dating. If a woman has the slightest flaw, like no jaw for example, or God forbid a crooked nose, men have an endless supply of internet sites and internet women to replace her. The fantasy is better than the reality but the reality is worse than the phobia. Now let us examine the spiritual reasons that men cheat. According to the famed psychiatrist M. Scott Peck M.D. in his books “People of the Lie” and “Glimpses of the Devil”, in addition to the holy white angel spirit in every person all of our bodies are also containers for evil spirits that resemble the alien monster in the movie Independence Day. Inwardly we are all monsters who sacrificed our first born children alive by fire as the drummers beat their drums loudly to drown out the terrified screams of our burning babies which we sacrificed to the God Baal, Beelzebub, Satan on fire altars in Gehenna just south of Jerusalem for thousands of years up until 2,000 years ago on a planet 5 billion years old. Our ancestors were murderous freaks and we are their clones and this is the reason men cheat. penile enlargment surgeries penis enargement traction device penis enhancement picture compare penile enlargement pills pennis enlargement exercise penis girth enargement penis elargement fact penis enlagement fact best enlargement exercise penile

In the United States, herpes simplex is the most common genital infection. Estimates show that about 1 million people annually will be infected by this virus. Recurrent infections, as a result of the virus, will affect about 45 million people every year. Studies add that the incidence of herpes simplex will be higher in young adults, adolescents, and in those living in lower socioeconomic populations. It is a chronic disease and, in many people, will not have any visible symptoms. Currently, no total cure is available for herpes simplex. Herpes simplex is the result of either one of two viruses, herpes simplex virus type 1 (HSV-1), or herpes simplex virus type 2 (HSV-2). However, most herpes infections are caused by HSV-2. It has been estimated that HSV-2 is responsible for 80% of initial herpes infections, and up to 95% of recurrent infections. What Are The Symptoms Of Herpes Simplex? While many people experience no symptoms with herpes simplex, painfully frequent recurrences of herpes symptoms will appear in others. Approximately 3 to 7 days after contacting the infection symptoms of herpes simplex will begin to appear. Red spots, that will be painful, will appear in the genital area. For men, these lesions will generally appear on the head, or the shaft of the penis. For women, these lesions will most commonly occur outside of the vaginal opening, inside the vagina, and on the cervix. These spots will soon form painful blisters filled with a clear fluid containing particles of the herpes virus. When the blisters break they will shed the virus, causing the appearance of painful ulcers. These ulcers will last up to 6 weeks. Should the ulcers become infected, they could last considerably longer. Touching these blisters, and then touching other areas of the body can spread this infection to these other areas. Persons with the herpes simplex virus will also experience headache, fever, enlargement of lymph nodes, painful urination, and urinary retention. Men may also experience a urethral discharge, while women may experience a vaginal discharge. While men are unlikely to experience further serious complications of the herpes simplex, women with herpes simplex may experience complications when pregnant. Although not yet conclusively established, many believe that there may be a direct link between herpes simplex and cervical cancer. In rare cases, the herpes virus may spread to the brain. This will cause a condition called herpes encephalitis, a life-threatening condition. Although treatment with the drug acyclovir (Zovirax), an antiviral drug, is capable of curing the encephalitis, up to 60% of the survivors will sustain some sort of permanent brain damage. What Is The Treatment For Herpes Simplex? While the herpes simplex virus cannot be cured, the symptoms can be alleviated. The drug Acyclovir helps to reduce the severity of the initial episode, and is also administered to treat subsequent episodes. Acyclovir is administered for 7 to 10 days until the lesions fully heal. How Can Herpes Simplex Be Prevented? The best way to prevent herpes simplex is to avoid unprotected sex. Herpes simplex may be transmitted through genital-genital contact, but it is important to remember that it may also be transmitted through oral-genital contact. Condoms are usually recommended to prevent transmission of herpes simplex. However, not all of the lesions may be covered by the condom. Any person engaging in sexual activity with a person infected with herpes simplex, must refrain from touching any lesions, especially uncovered lesions. The person infected with herpes simplex must also avoid touching any lesions to eliminate the possibility of spreading the infection to other parts of their bodies. Because there is no cure, prevention is especially important for herpes simplex. Currently, The National Institute of Health is testing an HSV-2 vaccine. However, its use is limited to women who have no history of HSV-1 exposure. For now, safe sex practices are the best way to prevent the spread of this highly infectious disease. penile enlargement fact penis enlagement pic before and after penis enlargment supplement vimax extender vimax enlargement manhattan penis surgeon natural penis enlargment technique pnis enlargement pic before and after penis enlagement herb best enlargement exercise penile

Male breast enhancement involves both breast reduction as well as breast enlargement. There are several reasons that a man would choose some form of breast enhancement. In obese men, excess tissue accumulates over the pectoral region, giving an impression of feminine breasts. Also men who have higher levels of estrogen in their bodies have a tendency to have bigger breasts. These can now be surgically corrected by an operation called gynecomastia that is similar to liposuction. The surgeon makes an incision near the armpit and the extra tissue is disintegrated and withdrawn through it. This operation requires hospitalization for one or two days and is performed under anesthesia. Some men with small pectoral muscles go for breast enlargement. Breast enlargement provides a contour to the pectoral area in men who are devoid of it. This is an implant operation similar to that done in women. The difference is that the silicone implant is much harder and there is no question of leakage. This is usually an outpatient operation that lasts only a couple of hours and the patient can resume work within a week. As in women, there are herbal methods such as pills, capsules, and creams available for breast enlargement in men, but they do not work as effectively in men as they are specifically designed for female hormones. Exercise is another natural breast enlargement procedure implemented by many men. The perspective regarding male breast enhancement is changing. In 2004 alone, there were about 14000 men in the US who went under the knife for gynecomastia. That makes breast enhancement surgery the fifth most popular cosmetic surgery in American males. Some men even get the skin around their areolas folded to make their nipples seem smaller. It is important to note that men who undergo breast enlargement have to wear bras till their new tissue settles with the older one. Men who have breast enhancement surgeries done claim that it boosts their self-confidence. They are more at ease on beaches and in locker rooms. The notable point is that breast enhancement is not just a woman’s field anymore.